Introduction | Installation | Gene expression modeling in context of rinderpest infection | Computational resources consideration | Parallel computing | Constructing molecular signatures

Exploring the data in xcoredata

Introduction | Data import and sanity check | HLA association analysis | Are classical HLA alleles associated with disease status? | HLA association fine-mapping on amino acid level | Can we find evidence for a role of HLA variation related to NK cell interactions? | KIR associations and HLA-KIR interactions | Do we see association on the level of KIR genes, and when considering defined HLA-KIR interactions? | HLA-KIR interactions | Do known biological interactions between KIR receptors and their HLA ligands show significant assocation? | HLA heterozygosity and evolutionary divergence

Introduction | Quick start | Reading input data | Creating midas objects | MiDAS object | Association analysis | Model definition | Running analysis